Antibacterial Hand Sanitizer from Seaweed Extract Combination (Eucheuma spinosum and Eucheuma cottonii)

March 20, 2020

One of the primary methods of reducing the spread of germs and diseases is the use of proper hand care and sanitation. This is especially true in areas where bacterial contamination is particularly problematic such as coronavirus pandemic cases are increasingly overwhelmed. While using hand sanitizer is a smart way to slow and prevent the spread of viruses, handwashing with Soap and water is commonly used, but hand sanitizers that do not need to be washed off have become popular as well. The user applies the hand sanitizer onto the hands and spreads it around such that the hand sanitizer contacts most or all of the skin on the hands.

Hand sanitizers are available in gels or foams, and many include antimicrobial agents. One Such antimicrobial agent is alcohol, and alcohol-based hand sanitizing products are known and in use. Hand sanitizer gel formulation containing combinations of Eucheuma spinosum and Eucheuma cottonii seaweed extract, research by Students Pharmacy from Halu Oleo University, Southeast Sulawesi, Indonesia. Seaweed was extracted by maceration method using methanol as a solvent. The combination of extracts at concentrations of 4% with a ratio of 1: 1 determined the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). The combination of extracts that can kill bacteria was formulated into a hand sanitizer gel preparation using a carbopol as base of gel by mechanical dispersion method. Antibacterial activity of gel against the bacteria S. aureus and E. coli using the dilution method.

The results obtained by the MIC value for S. aureus bacteria is 2% and 4% for E. coli bacteria. MBC value of the combination of extracts against S. aureus and E. coli bacteria was 4%. Gel preparations were obtained in the form of semisolid, green, clear, green tea scent, and pH 6.3 and 5.7. (Akib et al., 2019.) The additional thickener formulation in alcohol gel and sanitizer may increase viscosity and suspension, can produce a gel or a gel-type hand sanitizer, and limit the evaporation rate of the alkyl monoalcohol in some embodiments. (Luciow et al.,2017). On the other hand, the combination of seaweed extract is suitable for all skin types, restore the natural balance of pH levels, and can exhibit bactericidal activity.

Source :

http://ojs.uho.ac.id/index.php/jfp/article/view/9232

https://patents.google.com/patent/US20170181429A1/en